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Chinese Journal of Geriatrics Research(Electronic Edition) ›› 2014, Vol. 01 ›› Issue (01): 24-26. doi: 10.3877/cma.j.issn.2095-8757.2014.01.007

Special Issue:

• Clinical Research • Previous Articles     Next Articles

The correlation of gastroparesis and postprandial blood glucose in elderly patients with type 2 diabetes mellitus

Qingqing Wang1, Beibei Zhang1, Cen Lou2   

  1. 1. Endocrinology Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China
  • Received:2014-08-15 Online:2014-11-30 Published:2014-11-30

Abstract:

Objective

To investigate the relationship between gastroparesis and PBG in elderly patients with T2DM.

Methods

Eighty patients were devided into 2 groups: non-elderly DM group (n=22, <60 years old) and elderly DM group (n=58, ≥60 years old). Twenty health participants were used as the control group. Half time gastric emptying of liquid and solid (T1/2), fasting blood sugar, 1 h, 2 h and 3 h PBG, HbA1c and 24 h urine protein were evaluated by SPECT technics.

Results

Half time gastric emptying of solid (T1/2) of non-elderly DM group and elderly DM group were significantly higher than control group (t=3.56、9.36, P<0.05 or 0.01). The delay rate of solid phase of elder DM group is significantly higher than non-elderly DM group (t=5.21, P<0.05). T1/2, fasting blood sugar, 2 h and 3 h PBG, HbA1c and 24 h urine protein of elderly DM group is significantly higher than non-elderly DM group (t=2.67、3.12、3.43, P<0.05 or 0.01). The peak time of blood sugar of elder diabetics was in 3-hour after meals.

Conclusion

Diabetic gastroparesis is a common chronic complication of T2DM, the incidence of gastroparesis is high. Doctors should pay attention to the delayed peak time of PBG.

Key words: Diabetes mellitus, type 2, Gastroparesis, Gastric emptyinge, Standard meal, SPECT imaging technics

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