Application of concentrated growth factor in wound care of elderly patients

doi:10.3877/cma.j.issn.2095-8757.2023.04.006

Abstract

Abstract:

Objective

To investigate the effect of concentrated growth factor (CGF) on wound healing in elderly patients.

Methods

A total of 44 elderly patients with poor wound healing admitted to Zhejiang Hospital from September 2017 to August 2021 were enrolled, of which 22 were treated with conventional wound care (control group) and the remaining 22 patients were treated with CGF (observation group). The wound healing time, pain visual analogue score (VAS) and clinical efficacy of the two groups were compared. The t test was used for the comparison of the measurement data, and the chi-square test was used for the comparison of the counting data.

Results

The healing time of the observation group was significantly shorter than that of the control group, and the pain VAS was significantly lower than that of the control group (t=2.989, 10.959, P < 0.01). The total effective rate of the patients in the observation group was significantly higher than that in the control group, but the difference was not statistically significant (χ²=2.230, P > 0.05).

Conclusion

Compared with conventional nursing, CGF has a better clinical effect on poor wound healing in the elderly, and its operation is simple and easier to care, which is worthy of promotion.

Key words: Concentrated growth factor, Aged, Wound, Nursing

Shuhong Ge, Qiming Zhao, Chunyan Huang, Xiaoping Chen, Qingwei Ye, Fei Li. Application of concentrated growth factor in wound care of elderly patients[J]. Chinese Journal of Geriatrics Research(Electronic Edition), 2023, 10(04): 36-39.

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References 14

[1]	陈群，吴红.老年难愈性创面的个性化护理[J].中华损伤与修复杂志，2018，13(1):75-78.
[2]	Koivuniemi R, Hakkarainen T, Kiiskinen J, et al. Clinical study of nanofibrillar cellulose hydrogel dressing for skin graft donor site treatment[J]. Advances in wound care, 2020, 9(4):199-210.
[3]	陈诺，李羽霖，阮琼芳，等．浓缩生长因子及其在促进损伤组织修复中的应用进展[J]．中华损伤与修复杂志，2021，16(6):520-524.
[4]	张硕.CGF在糖尿病足溃疡创面治疗中的效果观察[J].中国实用医药，2021，16(35):85-87.
[5]	Kao CH. Use of concentrate growth factors gel or membrane in chronic wound healing: Descriptionof 18 cases[J]. Int Wound J, 2020, 17(1):158-166.
[6]	Amato B, Farina MA, Campisi S, et al. CGF treatment of leg ulcers: A randomized controlled trial[J]. Open Medicine, 2019, 14(1):959-967.
[7]	Zhao Q, Gao J, Huang X, et al. Concentrated growth factors extracted from blood plasma used to repair nasal septal mucosal defect after rhinoplasty[J]. Aesthetic Plastic Surgery, 2019, 44(2):1-6.
[8]	汪淼，赵启明，陆海山，等.CGF在多种类型创面修复中的临床应用[J].中国美容医学，2020，29(4):75-78.
[9]	Tian J, Cheng LH, Cui X, et al. Application of standardized platelet-rich plasma in elderly patientswith complex wounds[J]. Wound Repair Regen, 2019, 27(3):268-276.
[10]	Pinto NR, Ubilla M, Zamora Y, et al. Leucocyte- and platelet-rich fibrin (L-PRF) as a regenerative medicine strategy for the treatment of refractory leg ulcers: A prospective cohort study[J]. Platelets, 2018, 29(5):468-475.
[11]	Yu P, Zhai Z, Jin X, et al. Clinical application of platelet-rich fibrin in plastic and reconstructive surgery: A systematic review[J]. Aesthetic Plastic Surgery, 2018, 42(2):511-519.
[12]	Prabhu R, Vijayakumar C, Bosco CA, et al. Efficacy of Homologous, Platelet-rich plasma dressing in chronic non-healing ulcers: An observational study[J]. Cureus, 2018, 10(2):e2145.
[13]	Abdullah BJ, Atasoy N, OMER AK. Evaluate the effects of platelet rich plasma (PRP) and zincoxide ointment on skin wound healing[J]. Ann Med Surg (Lond), 2018, 37:30-37.
[14]	Yamakawa S, Hayashida K. Advances in Surgical Applications of Growth Factors for Wound Healing[J]. Burns & Trauma, 2019, 7(1):1-13.

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