Research progress of adrenal crisis

doi:10.3877/cma.j.issn.2095-8757.2021.01.011

Abstract

Abstract:

Adrenal crisis is a series of clinical symptoms caused by deficiency or absence of adrenocortical hormone secretion for various reasons, mainly manifested as the related symptoms caused by deficiency of adrenocortical hormone.The condition of adrenal crisis is more critical, and the patients with hypoadrenal function should be paid special attention, and timely diagnosis and treatment should be given to prevent the condition from deteriorating rapidly and threatening life.In this paper, the definition, epidemiological characteristics, etiology, clinical manifestations, prevention strategies and the latest recommendations of AC will be reviewed, with a view to providing help for the clinical understanding of adrenal crisis.

Key words: Adrenal crisis, Risk factors, Clinical manifestation, Treatment, Management

Yu Zhang, Jinbin Pan, Huining Yu, Lin Wang, Xin Li. Research progress of adrenal crisis[J]. Chinese Journal of Geriatrics Research(Electronic Edition), 2021, 08(01): 45-48.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhlnbyjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-8757.2021.01.011

https://zhlnbyjdzzz.cma-cmc.com.cn/EN/Y2021/V08/I01/45

Figures/Tables 1

References 24

[1]	Hahner S. Acute adrenal crisis and mortality in adrenal insufficiency: Still a concern in 2018[J]! Ann Endocrinol (Paris), 2018, 79(3):164-166.
[2]	Bouillon R. Acute adrenal insufficiency[J]. Endocrinol Metab Clin North Am, 2006, 35(4):767-775.
[3]	Troy HK Puar, Nike MML Stikkelbroeck, Lisanne CCJ Smans, et al. Adrenal crisis: Still a deadly event in the 21st century[J]. Am J Med, 2016, 129(3):339.e1-9.
[4]	Katherine G White. A retrospective analysis of adrenal crisis in steroid-dependent patients: causes, frequency and outcomes[J]. BMC Endocr Disord, 2019, 19(1):129.
[5]	Allolio B. Extensive expertise in endo crinology: Adrenal crisis[J]. Eur J Endocrinol, 2015, 172(3):R115-124.
[6]	Baloch HM, Grice-Patil ZJ, Selig DJ, et al. Recognition and treatment of adrenal insufficiency secondary to abiraterone: A case report and literature review [J]. Oncology, 2019, 97(5):301-305.
[7]	Hahner S, Spinnler C, Fassnacht M, et al. High incidence of adrenal crisis in educated patients with chronic adrenal insufficiency: a prospective study[J]. J Clin Endocrinol Metab, 2015, 100(2):407-416.
[8]	Ramamoorthy S, Cidlowski JA. Corticosteroids: Mechanisms of action in health and disease[J]. Rheum Dis Clin North Am, 2016, 42(1):15-31.
[9]	Amrein K, Martucci G, Hahner S. Understanding adrenal crisis[J]. Intensive Care Med, 2018, 44(5):652-655.
[10]	Dineen R, Stewart PM, Sherlock M. Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy[J]. Clin Endocrinol (Oxf), 2019, 90(1):3-14.
[11]	Falhammar H, Frisén L, Norrby C, et al. Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency[J]. J Clin Endocrinol Metab, 2014, 99(12):E2715-2721.
[12]	Rushworth RL, Torpy DJ, Falhammar H. Adrenal crises: Perspectives and research directions[J]. Endocrine, 2017, 55(2):336-345.
[13]	Rushworth RL, Torpy DJ. A descriptive study of adrenal crises in adults with adrenal insufficiency: Increased risk with age and in those with bacterial infections[J]. BMC EndocrDisord, 2014, 14:79.
[14]	Iwasaku M, Shinzawa M, Tanaka S, et al. Clinical characteristics of adrenal crisis in adult population with and without predisposing chronic adrenal insufficiency: A retrospective cohort study[J]. BMC Endocr Disord, 2017, 17(1):58.
[15]	Puar TH, Stikkelbroeck NM, Smans LC, et al. Adrenal crisis: Still a deadly event in the 21st century[J]. Am J Med, 2016, 129(3):339.e1-9.
[16]	Bornstein SR, Allolio B, Arlt W, et al. Diagnosis and treatment of primary adrenal insufficiency: An Endocrine Society clinical practice guideline[J]. J Clin Endocrinol Metab, 2016, 101(2):364-389.
[17]	Chrisp GL, Maguire AM, Quartararo M, et al. Variations in the management of acute illness in children with congenital adrenal hyperplasia: An audit of three paediatric hospitals[J]. Clin Endocrinol (Oxf), 2018, 89(5):577-585.
[18]	殷富存.肾上腺危象抢救1例[J].河北中西医结合杂志，1999，8(1):106-107.
[19]	陈霞，珠宝荣，海霞.肾上腺危象1例报告并文献复习[J].中国社区医师，2017，33(31):73-75.
[20]	Vindhyala MR, Boppanaa VS, Vindhya S. Takotsubo cardiomyopathy: Is it due to adrenal crisis or sjogren’s flare[J]? Cardiol Res, 2018, 9(6):378-380.
[21]	Hahner S, Loeffler M, Bleicken B, et al. Epidemiology of adrenal crisis in chronic adrenal insufficiency: The need for new prevention strategies[J]. Eur J Endocrinol, 2010, 162(3):597-602.
[22]	Arlt W, Society for Endocrinology Clinical Committee. Society for endocrinology endocrine emergency guidance: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients[J]. Endocr Connect, 2016, 5(5):G1-G3.
[23]	Dineen R, Thompson CJ, Sherlock M. Adrenal crisis: Prevention and management in adult patients[J]. Ther Adv Endocrinol Metab, 2019, 10:2042018819848218.
[24]	Kampmeyer D, Lehnert H, Moenig H, et al. A strong need for improving the education of physicians on glucocorticoid replacement treatment in adrenal insufficiency: An interdisciplinary and multicentre evaluation[J]. Eur J Intern Med, 2016, 33:e13-15.

Please choose a citation manager

Content to export