To to explore the therapeutic effect of comprehensive intervention measures under the guidance of comprehensive geriatric assessment (CGA) on senil sarcopenia in the elderly.

120 elderly patients with sarcopenia who were admitted to No.93 Hospital of the Joint Logistic Support Force from June to December 2018 were evaluated by using CGA software developed by Zhejiang Hospital. The control group (60 cases) was only treated with basic diseases, without sarcopenia intervention measures;The observation group received comprehensive intervention for sarcopenia according to CGA results while treating basic diseases, including exercise therapy, nutrition therapy, drug therapy, and management of life, environment, medication and psychology. Before treatment, 3 months and 6 months after treatment, the results of laboratory examination (including serum albumin, hemoglobin, fasting blood glucose, cholesterol, triglyceride and electrolytes such as sodium, potassium and calcium), body composition (including inorganic salt, protein, body fat, BMI and muscle mass index of extremities) and assessment of sarcopenia (including walking speed, body fat, body fat and muscle mass index of extremities) were observed. T test was used to compare the measurement data between groups, and the χ² test was used to compare the enumeration data. Repeated measure analysis of variance was used to compare continuous time point indicators between the two groups.

The albumin level, protein level, limb muscle mass index and walking speed in two groups had inter-group effects (F=3.783, 4.038, 61.114, 124.119, P < 0.05), and there were statistically significant differences in albumin level, protein level, limb muscle mass index and walking speed between two groups after 3 months and 6 months of treatment (P < 0.05). There was no inter-group effect in other indicators (P > 0.05).

Comprehensive intervention measures under the guidance of CGA are effective in the short-term treatment of senile sarcopenia, but the long-term treatment effect remains to be confirmed.