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Chinese Journal of Geriatrics Research(Electronic Edition) ›› 2018, Vol. 05 ›› Issue (04): 46-48. doi: 10.3877/cma.j.issn.2095-8757.2018.04.011

Special Issue:

• Review • Previous Articles    

Correlation between telomere and senescence and idiopathic pulmonary fibrosis

Nana Guo1, Xuejun Liu2,(), Yufeng Du2, Li Qian2, Xiaoyan Hao2, Lifang Liu2   

  1. 1. Shanxi Medical University, Taiyuan 030000, China
    2. Department of Geriatrics, the First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2018-02-01 Online:2018-11-28 Published:2018-11-28
  • Contact: Xuejun Liu
  • About author:
    Corresponding author: Liu Xuejun, Email:

Abstract:

With the advent of an aging society, the incidence of chronic diseases associated with aging is on the rise, and aging diseases have attracted widespread attention from many scholars at home and abroad. Idiopathic pulmonary fibrosis is a cell-replicating aging disease that is susceptible to age. Telomere and telomerase have been identified as one of the important mechanisms leading to aging, which plays an important role in the development and progression of lung aging and disease. Further research to understand the relationship between telomere and aging and idiopathic pulmonary fibrosis will contribute to the choice of clinical treatment options and provide a theoretical basis for improving disease outcome.

Key words: Telomere, Telomerase, Aging, Idiopathic pulmonary fibrosis

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