[1] |
Cookson WO, Moffatt MF. Bedside to gene and back in idiopathic pulmonary fibrosis[J]. N Engl J Med, 2013, 368(23):2228-2230.
|
[2] |
Fernandez IE, Eickelberg O. New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis[J]. Lancet, 2012, 380(9842):680-688.
|
[3] |
Uji M, Nakada A, Nakamura T. Intravenous administration of adipose-derived stromal cells does not ameliorate bleomycin-induced lung injury in rats[J]. Open Journal of Regenerative Medicine, 2013, 2(2):39-45.
|
[4] |
Diaz de Leon A, Cronkhite JT, Katzenstein AL, et al. Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations[J]. PloS One, 2010, 5(5):e10680.
|
[5] |
Sekaran VG, Soares J, Jarstfer MB. Structures of telomerase subunits provide functional insights[J]. Biochim Biophys Acta, 2010, 1804(5):1190-1201.
|
[6] |
Nicholls C, Pinto AR, Li H, et al. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component[J]. Proc Natl Acad Sci USA, 2012, 109(33):13308-13313.
|
[7] |
Olovnikov AM. A theory of marginotomy: the incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon[J]. J Theor Biol, 1973, 41(1):181-190.
|
[8] |
Fell CD, Martinez FJ, Liu LX, et al. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis[J]. Am J Respir Crit Care Med, 2010, 181(8):832-837.
|
[9] |
Bourgeron T. The Possible Interplay of Synaptic and Clock Genes in Autism Spectrum Disorders[J]. Cold Spring Harb Symp Quant Biol, 2007, 72(1):645-654.
|
[10] |
Cole DI, Legassie JD, Bonifacio LN, et al. New models of Tetrahymena telomerase RNA from Experimentally Derived Constraints and Modeling[J]. J Am Chem Soc, 2012, 134(49):20070-20080.
|
[11] |
Ramírez-Melgarejo, Antonio J. Por la grandeza de la patria: la biopolítica en la España de Franco[J]. Sociología Histórica, 2014, 4:551-559.
|
[12] |
Yamaguchi H, Calado RT, Ly H, et al. Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia[J]. N Engl J Med, 2005, 352(14):1413-1424.
|
[13] |
Liu G, Yang K, Burns S, et al. The S1P(1)-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells[J]. Nat Immunol, 2010, 11(11):1047-1056.
|
[14] |
Procaccini C, De Rosa V, Galgani M, et al. An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness[J]. Immunity, 2010, 33(6):929-941.
|
[15] |
Vulliamy T, Marrone A, Goldman F, et al. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita[J]. Nature, 2001, 413(6854):432-435.
|
[16] |
Vander Haar E, Lee SI, Bandhakavi S, et al. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40[J]. Nat Cell Biol, 2007, 9(3):316-323.
|
[17] |
Vannier JB, Sandhu S, Petalcorin MI, et al. RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication[J]. Science, 2013, 342(6155): 239-242
|
[18] |
Armanios MY, Chen JJ, Cogan JD, et al. Telomerase mutations in families with idiopathic pulmonary fibrosis[J]. N Engl J Med, 2007, 356(13): 1317-1326
|
[19] |
Tsakiri KD, Cronkhite JT, Kuan PJ, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase[J]. Proc Natl Acad Sci USA, 2007, 104(18): 7552-7557
|
[20] |
Lee J, Reddy R, Barsky L, et al.Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice[J]. Am J Physiol Lung Cell Mol Physiol, 2009, 296(1): L57-L70
|
[21] |
Faner R, Rojas M, Macnee W, et al. Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis[J]. Am J Respir Crit Care Med, 2012, 186(4): 306-313.
|
[22] |
Kraan JW, van den Blink B, van den Toorn LM, et al. Idiopathic pulmonary fibrosis: new insights[J]. Ned Tijdschr Geneeskd, 2015, 159:A8148.
|
[23] |
Alder JK, Chen JJ, Lancaster L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis[J]. Proc Natl Acad Sci USA, 2008, 105(35):13051-13056.
|
[24] |
Budd DC, Holmes AM. Targeting TGFβ superfamily ligand accessory proteins as novel therapeutics for chronic lung disorders[J]. Pharmacol Ther, 2012, 135(3):279-291.
|
[25] |
Kage H, Borok Z. EMT and interstitial lung disease: a mysterious relationship[J]. Curr Opin Pulm Med, 2012, 18(5):517-523.
|
[26] |
Liu T, Chung MJ, Ullenbruch M, et al. Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice[J]. J Clin Invest, 2007, 117(12):3800-3809.
|