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中华老年病研究电子杂志 ›› 2018, Vol. 05 ›› Issue (04) : 20 -24. doi: 10.3877/cma.j.issn.2095-8757.2018.04.005

所属专题: 专题评论 文献

临床研究

老年综合评估在慢性阻塞性肺疾病治疗中的应用
张艳汝1   
  1. 1. 830001 乌鲁木齐,新疆维吾尔自治区人民医院干部保健中心
  • 收稿日期:2018-06-18 出版日期:2018-11-28

Clinical application of comprehensive geriatric assessment in chronic obstructive pulmonary disease

Yanru Zhang1   

  1. 1. Department of Cadre Health Care Center, The Xinjiang Uygur Autonomous Region people's Hospital, Urumqi 830001, China
  • Received:2018-06-18 Published:2018-11-28
引用本文:

张艳汝. 老年综合评估在慢性阻塞性肺疾病治疗中的应用[J]. 中华老年病研究电子杂志, 2018, 05(04): 20-24.

Yanru Zhang. Clinical application of comprehensive geriatric assessment in chronic obstructive pulmonary disease[J]. Chinese Journal of Geriatrics Research(Electronic Edition), 2018, 05(04): 20-24.

目的

探讨老年综合评估在慢性阻塞性肺疾病(chronic obstructive pulmo-nary disease, COPD)治疗中的临床应用效果。

方法

选取2017年1月至2018年4月新疆维吾尔自治区人民医院收治的99例老年COPD患者,其中采用常规专科治疗48例(对照组),采用CGA干预治疗51例(观察组)。记录两组患者治疗前及出院后1个月的各项评估结果[包括基本日常生活活动能力(basic activity of daily living, BADL)、工具性日常生活能力(instrumental activity of daily living, IADL)、步态、跌倒、认知功能、焦虑、抑郁],以及治疗前及出院后3个月的COPD评估测试(COPD assessment test, CAT)结果,并随访出院后6个月内再次急性发作、再住院治疗、合并症、死亡、呼吸衰竭等不良事件的发生情况;以及一秒用力呼气容积占预计值的百分比(FEV1/FVC)及6 min步行试验(6MWT)等指标。

结果

与治疗前比较,两组患者治疗后BADL、IADL评分并无明显变化(均P>0.05),步态、跌倒、认知功能、焦虑、抑郁的评分均明显改善(均P<0.05)。治疗前,两组患者BADL、IADL、步态、跌倒、认知功能、焦虑、抑郁评分的差异无统计学意义(P>0.05),出院1个月后观察组步态、跌倒、认知功能、焦虑、抑郁评分均较对照组明显改善(均P<0.05)。治疗前,两组患者CAT评分的差异无统计学意义(P>0.05);治疗后,观察组患者症状、活动能力、社会影响、FEV1/FVC及6MWT的评分均较对照组明显改善(均P<0.05)。随访期间观察组患者再次急性发作、再住院治疗以及合并症的发生率明显低于对照组(均P<0.05)。

结论

对于老年COPD患者,建议尽早应用综合评估技术,根据评估结果采取有效干预,可最大限度地维持和改善其功能状况和生活质量。

Objective

To explore the clinical application of comprehensive geriatric assessment in the treatment of chronic obstructive pulmonary disease.

Methods

99 hospitalized elderly patients with chronic obstructive pulmonary disease (>60 years old) were randomly divided into routine treatment group (48 cases) and comprehensive assessment group (51 cases) in January 2017 to April 2018. We compare the general data of the subjects, the treatment effect of the two groups before and after the treatment, the slow lung assessment test, the 6 minute walk test, and the percentage of the one second forced expiratory volume.

Results

There was no significant difference in general data between the two groups (P>0.05). There was no statistically significant difference between the two groups before and after treatment (P>0.05). The differences in gait, fall, cognitive function, anxiety and depression were statistically significant (P<0.05). The routine treatment group was compared with the CGA group at admission, and the BADL, IADL, gait, and fall of the patients were compared. There was no significant difference in the difference of cognitive function, anxiety and depression (P>0.05). After 1 month of discharge, the difference of BADL and IADL in the CGA group was not statistically significant (P>0.05), but the difference in gait, fall, cognitive function, anxiety and depression was statistically significant (P<0.05). The test showed that before treatment, there was no significant difference in the therapeutic effect between the 2 groups (P>0.05), and after 1 month of discharge, the symptoms, activity, social influence, FEV1/FVC and 6MWT control groups in group CGA were statistically significant (P<0.05), but there was no significant difference in sleep (P>0.05). After the treatment of the 2 groups, the differences of reacute attack, rehospitalization and complication were statistically significant (P<0.05), and there was no significant difference between death and respiratory failure (P>0.05).

Conclusion

The comprehensive evaluation technique of old age has effect on the clinical treatment of chronic obstructive pulmonary disease. It is worth popularizing. It is suggested that the comprehensive evaluation technique should be applied as early as possible, and effective intervention should be taken to maintain and improve the functional status and quality of life of the elderly patients to the maximum.

表1 两组患者一般资料的比较(例)
表2 两组患者治疗前后各项评估结果的比较
表3 两组患者治疗前后CAT评分的比较(分)
表4 两组患者治疗后负性事件发生情况的比较[例(%)]
[1]
蹇在金.老年人综合评估[J].中华老年医学杂志,2012,31(3):177-181.
[2]
Ellis G, Whitehead MA, Robinson D, et al. Comprehensive geriatric assessment for older adults admitted to hospital: metaanalysis of randomised controlled trials[J]. BMJ, 2011, 343(2):6553.
[3]
Global Initiative for Chronic Obstructive Lung Disease(GOLD). Global strategy for the diagnosis, management, and prevention ofchronic obstructive pulmonary disease(Update 2017)[EB/OL].

URL    
[4]
Gladman JR. Delivering comprehensive geriatric assessment in new settings: advice for frontline clinicians[J]. J R Coll Physicians Edinb, 2016, 46(3):174-179.
[5]
Devore S, Parli SE, Oyler DR, et al. Comprehensive geriatric ass-essment for trauma: operationalizing the trauma quality improvement progr-am directive[J]. J Trauma Nurs, 2016, 23(6):337-342.
[6]
GOLD 2017 Global Strategy for the Diagnosis, Management and Preventio-n of COPD[EB/OL].[2017-01-03].

URL    
[7]
朱鸣雷,王秋梅,刘晓红,等.老年人综合评估[J].中华老年医学杂志,2015,34(7):709-710.
[8]
Shen S, He T, Chu J, et al. Uncontrolled hypertension and orthostatic hypotension in relation to standing balance in elderly hypertensive patients[J]. Clin Interv Aging, 2015, 28(5):897-906.
[9]
Chu JJ, Chen XJ, Shen SS, et al. A poor performance in comprehensive geriatric assessment is associated with increased fall risk in elders with hypertension: a cross-sectional study[J]. J Geriatr Cardiol, 2015, 12(2):113-118.
[10]
Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician[J]. J Psychiatr Res, 1975, 12(3):189-198.
[11]
de Craen AJ, Heeren TJ, Gussekloo J. Accuracy of the 15-item geriatric depression scale (GDS-15) in a community sample of the oldest old[J]. Int J Geriatr Psychiatry, 2003, 18(1):63-66.
[12]
老年医学专科医师教育委员会.老年医学专科医师必备的临床知识与技能[J].中华老年医学杂志, 2016, 35(6):569-571.
[13]
Alessi CA, Stuck AE, Aronow HU, et al. The process of care in preventivein-home comprehensive geriatric assessment[J]. J Am Geriatr Soc, 1997, 45(9):1044-1050.
[14]
In P, Wang H, Vos T, et a1. A subnational analysis of mortality and prevalenee of copd in china from 1990 to 2013: findings from the global burden of disease study 2013[J]. Chest, 2016, 150(6):1269-1280.
[15]
高晶晶,程意,罗勇.COPD常见共患病及其流行病学特点和临床意义[J].国际呼吸杂志,2017,37(1):70-75.
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