探讨影响老年压疮愈合的相关危险因素，并进行分析。

选取2013年3月至12月杭州市老年病医院收治的老年压疮患者99例，均采用综合治疗方案（外科清创+负压封闭引流+手术闭合创口），对其13项相关因素（年龄、糖尿病、低蛋白血症、血细菌培养阳性、心肺功能不全、肾功能不全、创面深度、骨髓炎、多发骨折、周围血管血运障碍、感觉障碍、自主运动障碍、痴呆症）进行单因素分析，筛选出危险因素，同时测定综合治疗期间（1、3、6、10周）创床局部组织氧饱和度（rSO₂）。两组间13项影响因素的单因素分析采用χ²检验，具有统计学意义的影响因素再行Logistic回归分析。

综合治疗后28例患者治疗失败。影响压疮愈合的主要危险因素有血白蛋白≤25 g/L、血细菌培养阳性、心肺功能不全和周围血管血运障碍，Logistic回归分析未发现上述四因素是导致压疮治疗失败的独立危险因素。压疮rSO₂检测结果显示，在综合治疗10周后，创床rSO₂提升达32%。

血细菌培养阳性、心肺功能不全、周围血管血运障碍、血白蛋白≤25 g/L是导致老年压疮治疗失败率增高的危险因素。

To explore the related risk factors of elderly patients with pressure healing.

99 elderly pressure ulcer patients from March to December 2013 who had received comprehensive treatment in the center were selected. The relevant factors (age, diabetes, hypoproteinemia, cardiopulmonary insufficiency, renal insufficiency, wound depth, osteomyelitis, multiple fracture, peripheral vascular hemodynamic disorder, disturbance of sensation,disturbance of autokinetic movement, dementia)that affect the failure of clinical treatment were analyzed and the statistically significant predictors were screened. Meanwhile, the partial tissue oxygen saturation (rSO₂) was measured during the comprehensive treatment (week 1, 3, 6, 10). Single factor analysis of related factors between two groups used –chi-square test, the related factors which were statistically significant took logistic regression.

28 out of 99 cases were failure in comprehensive treatment group. The major risk factors of pressure ulcer healing include blood albumin≤ 25 g/L, blood culture positive, cardiopulmonary dysfunction and peripheral vascular blood circulation disorder. These factors were correlated with treatment failure. According to Logistic retrospective analysis, these four factors are not independent factorsleading to the failure of pressure ulcer treatment. After 10 weeks of treatment, the test of rSO₂in wounds improved to 32%.

Blood culture positive,cardiopulmonary dysfunction, peripheral vascular blood circulation disorder and blood albumin≤25 g/Lmay lead to the increasing of failure rate for treatment of pressure ulcer in elderly patients.