| [1] |
Boutet MA, Nerviani A, Fossati-Jimack L, et al. Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features[J]. Osteoarthritis Cartilage, 2024, 32(2):166-176.
|
| [2] |
国家心血管病中心，中国心血管健康与疾病报告编写组.中国心血管健康与疾病报告2023概要[J].中国循环杂志，2024，39(7)：625-660.
|
| [3] |
Yu F, Xia W. The epidemiology of osteoporosis, associated fragility fractures, and management gap in China[J]. Arch Osteoporos, 2019, 14(1):32.
|
| [4] |
Pan XB, Ma QY, Gao T, et al. Osteoporosis risk and its association with all-cause and cause-specific mortality among the elderly: A 16-year nationwide cohort study [J]. BMC Geriatr, 2025, 25(1):199.
|
| [5] |
Pan J, Zou Y, Zhang Q, et al. Mortality risk in osteoarthritis patients: A meta-analysis of observational studies[J]. BMC Musculoskelet Disord, 2025, 26(1):1102.
|
| [6] |
Wright VJ, Schwartzman JD, Itinoche R, et al. The musculoskeletal syndrome of menopause[J]. Climacteric, 2024, 27(5):466-472.
|
| [7] |
Wu X, Zhang M. Effects of androgen and progestin on the proliferation and differentiation of osteoblasts[J]. Exp Ther Med, 2018, 16(6):4722-4728.
|
| [8] |
Deng C, Presle N, Pizard A, et al. Beneficial impact of eicosapentaenoic acid on the adverse effects induced by palmitate and hyperglycemia on healthy rat chondrocyte[J]. Int J Mol Sci, 2024, 25(3):1810.
|
| [9] |
Engin A. Reappraisal of adipose tissue inflammation in obesity[J]. Adv Exp Med Biol, 2024, 1460:297-327.
|
| [10] |
Zhang S, Hao W, Chen D, et al. Intermittent administration of PTH for the treatment of inflammatory bone loss does not enhance entheseal pathological new bone formation[J]. Biochem Biophys Res Commun, 2024, 711:149888.
|
| [11] |
Torremadé N, Bozic M, Panizo S, et al. Vascular calcification induced by chronic kidney disease is mediated by an increase of 1α-hydroxylase expression in vascular smooth muscle cells [J]. J Bone Miner Res, 2016, 31(10):1865-1876.
|
| [12] |
De La Guía-Galipienso F, Martínez-Ferran M, Vallecillo N, et al. Vitamin D and cardiovascular health[J]. Clin Nutr, 2021, 40(5):2946-2957.
|
| [13] |
Zhang HN, Xu QQ, Thakur A, et al. Endothelial dysfunction in diabetes and hypertension: Role of microRNAs and long non-coding RNAs[J]. Life Sci, 2018, 213:258-268.
|
| [14] |
Li Q, Fu J, Park K, et al. Insulin receptors in vascular smooth muscle cells regulate plaque stability of atherosclerosis[J]. Cardiovasc Res, 2024, 120(16):2017-2030.
|
| [15] |
Guo X, Liu S, Wu X, et al. Alleviating vascular calcification with Bushen Huoxue formula in rats with chronic kidney disease by inhibiting the PTEN/PI3K/AKT signaling pathway through exosomal microRNA-32[J]. J Pharm Pharmacol, 2025, 77(4):550-563.
|
| [16] |
Zuccolo E, Badi I, Scavello F, et al. The microRNA-34a-Induced senescence-associated secretory phenotype (sasp) favors vascular smooth muscle cells calcification[J]. Int J Mol Sci, 2020, 21(12):4454.
|
| [17] |
Catheline SE, Bell RD, Oluoch LS, et al. IKKβ-NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice[J]. Sci Signal, 2021, 14(701):eabf3535.
|
| [18] |
Fang G, Li X, Yang F, et al. Amentoflavone mitigates doxorubicin-induced cardiotoxicity by suppressing cardiomyocyte pyroptosis and inflammation through inhibition of the STING/NLRP3 signalling pathway[J]. Phytomedicine, 2023, 117:154922.
|
| [19] |
Sun S, Ji Z, Fu J, et al. Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway[J]. Environ Sci Pollut Res Int, 2020, 27(21):26163-26171.
|
| [20] |
Hussain S, Sun M, Guo Y, et al. SFMBT2 positively regulates SOX9 and chondrocyte proliferation[J]. Int J Mol Med, 2018, 42(6):3503-3512.
|
| [21] |
Sproston NR, Ashworth JJ. Role of C-Reactive Protein at Sites of Inflammation and Infection[J]. Front Immunol, 2018, 9:754.
|
| [22] |
Li R, Kato H, Fumimoto C, et al. Essential amino acid starvation-induced oxidative stress causes DNA damage and apoptosis in murine osteoblast-like cells[J]. Int J Mol Sci, 2023, 24(20):15314.
|
| [23] |
Morgan MJ, Liu ZG. Crosstalk of reactive oxygen species and NF-κB signaling[J]. Cell Res, 2011, 21(1):103-115.
|
| [24] |
Shimura D, Shaw RM. GJA1-20k and mitochondrial dynamics[J]. Front Physiol, 2022, 13:867358.
|
| [25] |
Liu L, Zhang W, Liu T, et al. The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stress[J]. Redox Biol, 2023, 62:102663.
|
| [26] |
Lee WC, Guntur AR, Long F, et al. Energy metabolism of the osteoblast: Implications for osteoporosis[J]. Endocr Rev, 2017, 38(3):255-266.
|
| [27] |
Li X, Chen M, Chen X, et al. TRAP1 drives smooth muscle cell senescence and promotes atherosclerosis via HDAC3-primed histone H4 lysine 12 lactylation[J]. Eur Heart J, 2024, 45(39):4219-4235.
|
| [28] |
Kalucka J, Bierhansl L, Conchinha NV, et al. Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis[J]. Cell Metab, 2018, 28(6):881-894.
|
| [29] |
Tyrrell DJ, Blin MG, Song J, et al. Age-associated mitochondrial dysfunction accelerates atherogenesis[J]. Circ Res, 2020, 126(3):298-314.
|
| [30] |
Ramasamy SK, Kusumbe AP, Schiller M, et al. Blood flow controls bone vascular function and osteogenesis[J]. Nat Commun, 2016, 7:13601.
|
| [31] |
Liu Y, Chen P, Hu B, et al. Excessive mechanical loading promotes osteoarthritis development by upregulating Rcn2[J]. Biochim Biophys Acta Mol Basis Dis, 2024, 1870(6):167251.
|
| [32] |
Sun L, Wang Y, Kan T, et al. Elevated expression of Piezo1 activates the cGAS-STING pathway in chondrocytes by releasing mitochondrial DNA[J]. Osteoarthritis Cartilage, 2025, 33(5):601-615.
|
| [33] |
Kageyama A, Matsui H, Ohta M, et al. Palmitic acid induces osteoblastic differentiation in vascular smooth muscle cells through ACSL3 and NF-κB, novel targets of eicosapentaenoic acid[J]. PLoS One, 2013, 8(6):e68197.
|
| [34] |
Chen D, Li Y, Zhou Z, et al. HIF-1α inhibits Wnt signaling pathway by activating Sost expression in osteoblasts[J]. PLoS One, 2013, 8(6):e65940.
|
| [35] |
Liu L, Yuan W, Wang J. Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress[J]. Biomech Model Mechanobiol, 2010, 9(6):659-670.
|
| [36] |
Andreev D, Liu M, Weidner D, et al. Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin[J]. J Clin Invest, 2020, 130(9):4811-4830.
|
| [37] |
Millerand M, Berenbaum F, Jacques C. Danger signals and inflammaging in osteoarthritis[J]. Clin Exp Rheumatol, 2019, 37 Suppl 120(5):48-56.
|
| [38] |
Sohn R, Assar T, Kaufhold I, et al. Osteoarthritis patients exhibit an autonomic dysfunction with indirect sympathetic dominance[J]. J Transl Med, 2024, 22(1):467.
|
| [39] |
Spindler JS, Henning RJ. The critical role of inflammation in atherosclerotic coronary artery heart disease[J]. Curr Probl Cardiol, 2026, 51(7):103261.
|
| [40] |
Hashimoto K, Akagi M. The role of oxidation of low-density lipids in pathogenesis of osteoarthritis: A narrative review[J]. J Int Med Res, 2020, 48(6):300060520931609.
|
| [41] |
Dessalles CA, Leclech C, Castagnino A, et al. Integration of substrate- and flow-derived stresses in endothelial cell mechanobiology[J]. Commun Biol, 2021, 4(1):764.
|
| [42] |
Tootsi K, Märtson A, Zilmer M, et al. Increased arterial stiffness in patients with end-stage osteoarthritis: A case-control study[J]. BMC Musculoskelet Disord, 2016, 17:335.
|
| [43] |
Liu S, Deng Z, Chen K, et al. Cartilage tissue engineering: From proinflammatory and anti-inflammatory cytokines to osteoarthritis treatments (Review)[J]. Mol Med Rep, 2022, 25(3):12615.
|
| [44] |
Van Der Kraan PM. Differential role of transforming growth factor-beta in an osteoarthritic or a healthy joint[J]. J Bone Metab, 2018, 25(2):65-72.
|
| [45] |
Olansen J, Aaron RK. Similar Pathophysiological mechanisms between osteoarthritis and vascular disease[J]. Front Biosci (Landmark Ed), 2024, 29(9):320.
|
| [46] |
Fernandes JC, Martel-Pelletier J, Pelletier JP. The role of cytokines in osteoarthritis pathophysiology[J]. Biorheology, 2002, 39(1-2):237-246.
|
| [47] |
Ertürk C, Altay MA, Bilge A, et al. Is there a relationship between serum ox-LDL, oxidative stress, and PON1 in knee osteoarthritis?[J]. Clin Rheumatol, 2017, 36(12):2775-2780.
|
| [48] |
Shang L, Wang W, Liu Y, et al. Circulating proteomics and risk of atrial fibrillation: A systematic review of cohort studies[J]. J Cell Mol Med, 2025, 29(15):e70760.
|
| [49] |
Yu ZC, Fu R, Li Y, et al. The STING inhibitor C-176 attenuates osteoclast-related osteolytic diseases by inhibiting osteoclast differentiation[J]. Faseb J, 2023, 37(4):e22867.
|
| [50] |
Yao C, Veleva T, Scott L, et al. Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation[J]. Circulation, 2018, 138(20):2227-2242.
|
| [51] |
Cao H, Wang J, Xi L, et al. Dysregulated atrial gene expression of osteoprotegerin/receptor activator of nuclear factor-κB (RANK)/RANK ligand axis in the development and progression of atrial fibrillation[J]. Circ J, 2011, 75(12): 2781-2788.
|
| [52] |
Kan S, Duan M, Liu Y, et al. Role of mitochondria in physiology of chondrocytes and diseases of osteoarthritis and rheumatoid arthritis[J]. Cartilage, 2021, 13(2 suppl):1102s-1121s.
|
| [53] |
Chang Y, Zou Q. Mitochondrial calcium homeostasis and atrial fibrillation: Mechanisms and therapeutic strategies review[J]. Curr Probl Cardiol, 2025, 50(3):102988.
|
| [54] |
Adamo L, Rocha-Resende C, Prabhu SD, et al. Reappraising the role of inflammation in heart failure[J]. Nat Rev Cardiol, 2020, 17(5):269-85.
|
| [55] |
Palumbo A, Atzeni F, Murdaca G, et al. The role of alarmins in osteoarthritis pathogenesis: HMGB1, S100B and IL-33[J]. Int J Mol Sci, 2023, 24(15):12143.
|
| [56] |
Lu J, Zhao Q, Wang L, et al. MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4[J]. iScience, 2024, 27(7):110163.
|
| [57] |
Andenæs K, Lunde IG, Mohammadzadeh N, et al. The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling[J]. PLoS One, 2018, 13(7):e0201422.
|
| [58] |
Zhao F, Bai Y, Xiang X, et al. The role of fibromodulin in inflammatory responses and diseases associated with inflammation[J]. Front Immunol, 2023, 14:1191787.
|
| [59] |
杨剑锋，郝琳，王岩，等.骨关节炎与心血管疾病交互影响的研究进展[J].基础医学与临床，2025，45(2)：148-153.
|
| [60] |
Shimizu H, Nakagami H, Osako MK, et al. AngiotensinⅡ accelerates osteoporosis by activating osteoclasts[J]. Faseb J, 2008, 22(7):2465-2475.
|
| [61] |
Ren J, Kitaura H, Noguchi T, et al. Exogenous angiotensin-(1-7) provides protection against inflammatory bone resorption and osteoclastogenesis by inhibition of TNF-α expression in macrophages[J]. Calcif Tissue Int, 2024, 115(4):432-444.
|
| [62] |
Mo C, Ke J, Zhao D, et al. Role of the renin-angiotensin-aldosterone system in bone metabolism[J]. J Bone Miner Metab, 2020, 38(6):772-779.
|
| [63] |
Delalio LJ, Sved AF, Stocker SD. Sympathetic nervous system contributions to hypertension: Updates and therapeutic relevance[J]. Can J Cardiol, 2020, 36(5):712-720.
|
| [64] |
Lean JM, Jagger CJ, Kirstein B, et al. Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation[J]. Endocrinology, 2005, 146(2):728-735.
|
| [65] |
Madhur MS, Lob HE, Mccann LA, et al. Interleukin 17 promotes angiotensinⅡ-induced hypertension and vascular dysfunction[J]. Hypertension, 2010, 55(2):500-507.
|
| [66] |
Peng R, Dong Y, Zheng M, et al. IL-17 promotes osteoclast-induced bone loss by regulating glutamine-dependent energy metabolism[J]. Cell Death Dis, 2024, 15(2):111.
|
| [67] |
Ilić K, Obradović N, Vujasinović-Stupar N. The relationship among hypertension, antihypertensive medications, and osteoporosis: A narrative review[J]. Calcif Tissue Int, 2013, 92(3):217-227.
|
| [68] |
Duang S, Zhang M, Liu C, et al. Parathyroid hormone-induced vascular smooth muscle cells calcification by endoplasmic reticulum stress[J]. J Physiol Pharmacol, 2022, 73(5):3.
|
| [69] |
Bao Z, Du J, Gao Y, et al. Egg yolk-derived peptide VPF orchestrates OPG/RANKL/RANK-Mediated signaling to suppress osteoclast differentiation and facilitate bone development in zebrafish[J]. ACS Omega, 2026, 11(25):37486-37499.
|
| [70] |
Zhang X, Sun Q, Xie X, et al. Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway[J]. J Orthop Surg Res, 2025, 20(1):403.
|
| [71] |
Lee HK, Notario GR, Won SY, et al. Elevated sclerostin levels contribute to reduced bone mineral density in non-ambulatory stroke patients[J]. Bone Rep, 2025, 25:101829.
|
| [72] |
Whitehead M, Faleeva M, Oexner R, et al. ECM Modifications driven by age and metabolic stress directly promote vascular smooth muscle cell osteogenic processes[J]. Arterioscler Thromb Vasc Biol, 2025, 45(3):424-442.
|
| [73] |
Capulli M, Paone R, Rucci N. Osteoblast and osteocyte: Games without frontiers [J]. Arch Biochem Biophys, 2014, 561:3-12.
|
| [74] |
Morrell NW, Bloch DB, Ten Dijke P, et al. Targeting BMP signalling in cardiovascular disease and anaemia[J]. Nat Rev Cardiol, 2016, 13(2):106-120.
|
| [75] |
Zhu D, Li X, Macrae VE, et al. Extragonadal effects of follicle-stimulating hormone on osteoporosis and cardiovascular disease in women during menopausal transition[J]. Trends Endocrinol Metab, 2018, 29(8):571-580.
|
| [76] |
Neumann E, Junker S, Schett G, et al. Adipokines in bone disease[J]. Nat Rev Rheumatol, 2016, 12(5):296-302.
|
| [77] |
Cao H, Li Q, Li M, et al. Osteoprotegerin/RANK/RANKL axis and atrial remodeling in mitral valvular patients with atrial fibrillation [J]. Int J Cardiol, 2013, 166(3):702-708.
|
| [78] |
Xi L, Cao H, Chen Y. OPG/RANK/RANKL axis in atrial fibrillation[J]. Cardiology, 2013, 125(3):174-175.
|
| [79] |
Pani P, Swalsingh G, Sadayappan S, et al. Emerging roles of micropeptides in calcium cycling dysregulation and atrial fibrillation: A review[J]. Int J Biol Macromol, 2026, 370:152923.
|
| [80] |
Guan Z, Yuan W, Jia J, et al. Bone mass loss in chronic heart failure is associated with sympathetic nerve activation[J]. Bone, 2023, 166:116596.
|
| [81] |
Xue L, Guan Q, Zhang L. Bone modelling and remodelling in cold environment[J]. Biomolecules, 2025, 15(4).
|
| [82] |
Zheng MH, Li FX, Xu F, et al. The interplay between the renin-angiotensin-aldosterone system and parathyroid hormone[J]. Front Endocrinol (Lausanne), 2020, 11:539.
|
| [83] |
Ge G, Li J, Wang Q. Heart failure and fracture risk: A meta-analysis[J]. Osteoporos Int, 2019, 30(10):1903-1909.
|
| [84] |
Loncar G, Cvetinovic N, Lainscak M, et al. Bone in heart failure[J]. J Cachexia Sarcopenia Muscle, 2020, 11(2):381-393.
|