分析我国75岁及以上老年人高收缩压所致脑卒中疾病负担及其趋势。

整理2019年全球疾病负担研究（GBD 2019）数据，采用Joinpoint回归模型对1990—2019年我国75岁及以上老年人高收缩压所致脑卒中死亡率和伤残调整生命年（DALY）进行分析。

1990—2019年，我国75岁及以上居民因高收缩压导致的脑卒中死亡数自221 019人上升至552 179人，但粗死亡率和DALY率分别从806.84/10⁵和10 694.21/10⁵下降至611.01/10⁵和7 967.83/10⁵。趋势分析发现，我国75岁及以上居民因高收缩压导致的脑卒中粗死亡率逐年下降0.86%，男性逐年下降0.36%，女性逐年下降1.38%（Z=-6.72、-3.08、-9.43，P<0.01）；DALY率逐年下降0.88%，男性DALY率逐年下降0.45%，女性DALY率逐年下降1.33%（Z=-7.16、-3.88、-9.91，P<0.01）；75岁以上老年人因高血压所致脑卒中粗死亡率和DALY率均高于65～75（不包含75）岁老年人，且DALY率降速较低（分别为-0.88%和-1.24%）。我国75岁及以上居民因高收缩压导致的脑卒中DALY率高于高、中、低社会人口指数（SDI）国家或地区，逐年下降百分比低于高SDI国家或地区，但高于中、低SDI国家或地区（中国：-0.88%，高SDI国家或地区：-3.57%，中等SDI国家或地区：-0.69%，低SDI国家或地区：-0.67%）。

我国75岁以上老年人因高收缩压导致的脑卒中疾病负担重且降速慢，应深入开展高龄险人群精准健康管理研究，以实现健康老龄化目标。

To analyze the disease burden of stroke due to high systolic blood pressure and its trend in residents aged 75 years and above in China.

Data from the Global Burden of Disease Study 2019 (GBD 2019) were collected and Joinpoint regression model was used to analyze the mortality rate and disability-adjusted life year (DALY) of stroke due to high systolic blood pressure in elderly people aged 75 years and above in China from 1990 to 2019.

From 1990 to 2019, the number of stroke deaths due to high systolic blood pressure in residents aged 75 years and above increased from 221 019 to 552 179, but the crude death rate and DALY rate declined from 806.84/10⁵ and 10 694.21/10⁵ to 611.01/10⁵ and 7 967.83/10⁵, respectively. Trend analysis found that the crude stroke mortality rate due to high systolic blood pressure among residents aged 75 years and above in China decreased by 0.86% per year, with 0.36% per year in men and 1.38% per year in women (Z=-6.72, -3.08, -9.43; P < 0.01); and the DALY rate decreased by 0.88% per year, with 0.45% per year in men and 1.33% per year in women (Z=-7.16, -3.88, -9.91; P < 0.01). Crude mortality and DALY rates for stroke due to hypertension were higher in residents aged 75 years and above compared with those between 65-<75 years old, and the DALY rate in residents aged 75 years and above decline at a lower rate (-0.88% and -1.24%, respectively). The DALY rate of stroke due to high systolic blood pressure among residents aged 75 years and above in China was higher than that of high, medium, and low social demographic index (SDI) countries or regions, and the percentage of year-on-year decline was lower than that of high SDI countries or regions, but higher than that of medium and low SDI countries or regions (China: -0.88%, high SDI countries or regions: -3.57%, medium SDI countries or regions: -0.69%, low SDI countries or regions: -0.67%).

The disease burden of stroke due to high systolic blood pressure in China's elderly is high and slow to decline, and research on precise health management of the elderly risk group should be carried out in depth to achieve the goal of healthy aging.