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中华老年病研究电子杂志 ›› 2018, Vol. 05 ›› Issue (03) : 45 -48. doi: 10.3877/cma.j.issn.2095-8757.2018.03.010

所属专题: 文献

综述

肺部疾病对肠黏膜屏障影响的研究进展
郭娜娜1, 刘学军2,(), 杜毓锋2, 郝小燕2, 钱力2   
  1. 1. 030000 太原,山西医科大学
    2. 030001 太原,山西医科大学第一医院老年病科
  • 收稿日期:2017-12-28 出版日期:2018-08-28
  • 通信作者: 刘学军
  • 基金资助:
    山西省重点研发计划(指南)项目(201603D321096)

Advances in the influence of lung diseases on intestinal mucosal barrier

Na'na Guo1, Xuejun Liu2,(), Yufeng Du2, Xiaoyan Hao2, Li Qian2   

  1. 1. Shanxi Medical University, Taiyuan 030000, China
    2. Department of Geriatrics, the First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2017-12-28 Published:2018-08-28
  • Corresponding author: Xuejun Liu
  • About author:
    Corresponding author: Liu Xuejun, Email:
引用本文:

郭娜娜, 刘学军, 杜毓锋, 郝小燕, 钱力. 肺部疾病对肠黏膜屏障影响的研究进展[J/OL]. 中华老年病研究电子杂志, 2018, 05(03): 45-48.

Na'na Guo, Xuejun Liu, Yufeng Du, Xiaoyan Hao, Li Qian. Advances in the influence of lung diseases on intestinal mucosal barrier[J/OL]. Chinese Journal of Geriatrics Research(Electronic Edition), 2018, 05(03): 45-48.

近年来,肺部常见疾病多伴随胃肠功能障碍,严重影响患者预后,探索肺部疾病与肠黏膜屏障的关系逐渐受到重视。本文现就肠黏膜屏障的组成(包括机械屏障、生物屏障、免疫屏障、化学屏障)以及肺部疾病(肺炎、哮喘、慢性阻塞性肺疾病、特发性肺纤维化)对肠黏膜功能影响的作用机制进行综述,旨在为临床早发现、早治疗胃肠功能障碍提供理论依据。

In recent years, common lung diseases are often accompanied by gastrointestinal dysfunction, which seriously affects the prognosis of patients. The relationship between lung diseases and intestinal mucosal barrier needs to be explored. This paper presents the composition of the intestinal mucosal barrier (including mechanical barriers, biological barriers, immune barriers, and chemical barriers), the effects and the mechanisms of lung diseases (pneumonia, asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis) on intestinal mucosal function. The review aims to provide a theoretical basis for early detection and early treatment of gastrointestinal dysfunction.

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